2,4-Butanedione, 1,1,1-trifluoro-4-(4-methoxyphenyl)-

2,4-Butanedione, 1,1,1-trifluoro-4-(4-methoxyphenyl)- - Names and Identifiers

Name	4,4,4-trifluoro-1-(4-methoxyphenyl)-1,3-butanedione
Synonyms	AKOS B006868 CHEMBRDG-BB 6872303 (4-METHOXYBENZOYL)-1,1,1-TRIFLUOROACETONE 4,4,4-Trifluoro-1-(methoxyphenyl)-1,3-butanedione 4-(4-METHOXYPHENYL)-1,1,1-TRIFLUORO-2,4-BUTANEDIONE 4,4,4-trifluoro-1-(4-methoxyphenyl)-1,3-butanedione 4,4,4-TRIFLUORO-1-(4-METHOXYPHENYL)-1,3-BUTANEDIONE 4,4,4-trifluoro-1-(4-methoxyphenyl)butane-1,3-dione 4,4,4-TRIFLUORO-1-(4-METHOXYPHENYL)BUTANE-1,3-DIONE 2,4-Butanedione, 1,1,1-trifluoro-4-(4-methoxyphenyl)-
CAS	15191-68-1
InChI	InChI=1/C11H9F3O3/c1-17-8-4-2-7(3-5-8)9(15)6-10(16)11(12,13)14/h2-5H,6H2,1H3

2,4-Butanedione, 1,1,1-trifluoro-4-(4-methoxyphenyl)- - Physico-chemical Properties

Molecular Formula	C11H9F3O3
Molar Mass	246.18
Density	1.285g/cm³
Melting Point	57 °C
Boling Point	309°C at 760 mmHg
Flash Point	136.2°C
Solubility	soluble in Methanol
Vapor Presure	0.000655mmHg at 25°C
Appearance	powder to crystal
Color	White to Orange to Green
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.462

2,4-Butanedione, 1,1,1-trifluoro-4-(4-methoxyphenyl)- - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

2,4-Butanedione, 1,1,1-trifluoro-4-(4-methoxyphenyl)- - Introduction

4,4,4-trifluoro-1-(4-methoxyphenyl)-1,3-butylenedione is an organic compound commonly abbreviated as PMB-TFP. The following is an introduction to its nature, use, preparation and safety information:

Nature:
4,4,4-trifluoro-1-(4-methoxyphenyl)-1,3-butylenedione is a colorless liquid. It has a low boiling point and a high ignition point at room temperature. It is mutually insoluble with most organic solvents and water, but can be dissolved in some polar organic solvents.

Use:
PMB-TFP are often used as reagents in organic synthesis, and are often used in the introduction and removal of protective groups in chemical synthesis. It can be used in acylation and condensation reactions and in the synthesis of pharmaceuticals and other organic compounds. In addition, it is also used in the preparation and surface modification of polymer materials.

Method:
The preparation of PMB-TFP is usually achieved by reacting 4-methoxybenzyl alcohol with trifluoroacetyl chloride. The reaction takes place in a reaction solvent and an appropriate amount of base is added to facilitate the reaction.

Safety Information:
PMB-TFP are irritating and corrosive, and exposure to or inhalation of its vapors may be harmful to the skin, eyes and respiratory system. Direct contact with it should be avoided and appropriate protective measures should be taken during use or operation, such as wearing chemical protective gloves, goggles and respiratory protective equipment. If ingested or inhaled, please seek medical treatment. When using and storing, it should be kept in a dry, well-ventilated place, and away from fire and high temperature.

Last Update：2024-04-09 20:52:54